Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
More than half a billion years ago on a frigid, ice-covered Earth, glaciers stirred up ingredients for complex life by bulldozing land minerals and then depositing them in the ocean, according to ...
This process is controlled by a large protein-RNA complex called the spliceosome. MIT biologists have now discovered a new layer of regulation that helps to determine which sites on the messenger ...
Spliceosome structures have been investigated extensively in the past decade, but most of the studies have been restricted to a handful of model organisms. New research by Lu et al, looks outside this ...
SINGAPORE – What began as a labour of love in designing Golden Mile Complex in the early 1970s comes full circle as an architectural love story about how Modernist buildings have a place in the ...
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Scientists are working across disciplines to render complex reality to scientific understanding. It has been the great triumph of the sciences to find consistent means of studying phenomena hidden by ...