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Enhancing the thermostability of enzymes without impacting their catalytic function represents an important yet challenging goal in protein engineering and biocatalysis. We recently introduced a novel ...
Get Instant Summarized Text (Gist) Analysis of cephalopods, Indo-European languages, and ancient enzymes indicates that evolutionary changes predominantly occur in rapid bursts during speciation ...
Merck, as it prepares a new version of its cancer blockbuster Keytruda, gets a boost in its patent dispute with Halozyme Therapeutics.
They found that the enzyme becomes functional through phosphorylation at a specific amino acid—serine 302. To test this, they engineered a mutant form of HSV-1 with altered serine 302, making ...
RufO is a unique cytochrome P450 enzyme (CYP) involved in the biosynthesis of rufomycin, an antituberculosis cyclic peptide featuring an unusual nitrated tyrosine. Recent studies have clarified RufO’s ...