We defined SERBP1’s interactome, uncovered novel roles in splicing, cell division and ribosomal biogenesis ... SMN1 brings together the complex and is essential for spliceosome assembly. Since motor ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

Research from Umeå University paves the way for a quantitative data analysis method to study the cell division process in ...

Researchers at the Heidelberg University Biochemistry Center (BZH) have succeeded for the first time in depicting a faultily "blocked" spliceosome at high resolution and reconstructing how it is ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Oxide-ion conductors are important energy materials. Here, the authors found a tellurite-based oxygen ion conductor highlighting the interplay of secondary bond interactions and Grotthuss-like ...