A team of researchers has identified a mechanism that regulates the production of two different proteins from the same gene.

For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

In a new development at CERN, researchers at the LHCb collaboration have determined the spin-parity of singly heavy charm ...

We characterized back-splicing cis- and trans-elements, and found viral circRNAs resistant to spliceosome perturbation and lacking canonical splice donor-acceptors. Subsequent loss-of-function studies ...

RALY was identified in the spliceosome complex and in the Drosha microprocessor complex. The m 6 A modification is found to alter RNA structure to enhance HNRNPC binding, and HNRNPA2B1 could bind to ...

After hours: March 21 at 7:59:24 PM EDT Loading Chart for C ...

Mar. 20, 2025 — The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for ...