Phys.org on MSN8d
The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA
is correctly assembled into mature mRNA. Splicing is a basic requirement for producing proteins that fulfill an organism's ...
The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
How Cells Avoid Errors When Manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
Armed robbery in Revesby8d
Spliceosome: Cells' Error-Free MRNA Production Explained
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
News Medical on MSN3d
Splicing twins: unravelling the secrets of the minor spliceosome complex
Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
Nature13d
Altered mRNA Expression due to Insertion or Substitution of Thymine at Position +3 of Two Splice-Donor Sites in the Androgen Receptor Gene
One mutation is an adenine to thymine transversion at position +3 of the intron 6 splice-donor site. Using LMSF mRNA, RT-PCR of a portion of the AR androgen-binding domain yielded a small amount ...
Healio1d
FDA approves Evrysdi tablets for spinal muscular atrophy
The FDA has approved Evrysdi in tablet form for patients with spinal muscular atrophy aged 2 years and older who weigh more ...
The American Journal of Managed Care3d
Risdiplam Tablet for Spinal Muscular Atrophy Receives FDA Approval
The 5 mg risdiplam tablet provides the same efficacy and safety for spinal muscular atrophy as the currently available oral ...
News Medical on MSN6d
Alternative RNA Splicing in Cardiac Diseases
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