A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

More information: Prashant Bhat et al, Genome organization around nuclear speckles drives mRNA splicing efficiency, Nature (2024). DOI: 10.1038/s41586-024-07429-6 Provided by California Institute ...

The FDA has approved Evrysdi in tablet form for patients with spinal muscular atrophy aged 2 years and older who weigh more ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

The 5 mg risdiplam tablet provides the same efficacy and safety for spinal muscular atrophy as the currently available oral ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

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