From 1969 to 1985 we discovered accessory spleens in 8 patients with chronic immune thrombocytopenic purpura (ITP) who relapsed or failed after splenectomy. Imaging of accessory spleen used a ...

Stimulating platelet production with romiplostim is an effective strategy for managing patients with ITP. Thrombocytopenias can be caused by increased platelet destruction, decreased platelet ...

Radiolabeled platelet survival studies cemented the dogma that ITP was primarily due to increased platelet removal by the spleen. Consistent with this idea, platelet transfusion, commonly used in ...

an oral spleen tyrosine kinase inhibitor, for treating thrombocytopenia in adult patients with chronic ITP. This approval marks a significant expansion in Kissei’s market presence, providing a ...