Sickle Cell Disease is a genetic blood disorder that ... including an increased risk of infections. The spleen, which plays a crucial role in filtering bacteria and supporting immune function ...

Sickle Cell Disease ... managing the disease and improving quality of life. Why are individuals with SCD more susceptible to infections? One of the most critical complications of SCD is functional ...

the company's oral spleen tyrosine kinase (SYK) inhibitor, in patients with sickle cell disease (SCD). The study is being sponsored by the National Heart, Lung, and Blood Institute (NHLBI), part ...

sickle cell disease (or trait), thalassaemia, or recent viral symptoms. Subjects then underwent a limited abdominal ultrasound examination, where splenic length and width were recorded. Results: Mean ...

Sickle cell disease starts damaging the organs in the first year of life. One of the first organs affected is the spleen. The spleen is a small organ on the left side of the abdomen underneath the ...

2 Department of Pathology and ... the brunt of the disease, resulting in diffuse alveolar damage (DAD), many other organs, including the heart, the kidneys, the hepatobiliary system, the central ...