TGF-β (transforming growth factor-β) is well identified as a central mediator in renal fibrosis. TGF-β initiates canonical and non-canonical pathways to exert multiple biological effects. Among them, ...

Cystic fibrosis (CF) treatment typically involves procedures and medications that help clear the airways. Other treatments may include antibiotics, pancreatic enzymes, a high-calorie diet, and ...

Feb. 6, 2025 — Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life ...

The transplantation of HMDMs via the spleen into an immunocompromised mouse model of liver fibrosis resulted in a regression of collagen and a reduction in markers of liver injury. These findings ...