The discovery of a novel class of peripheral tryptophan hydroxylase (TPH) inhibitors is described. This class of TPH inhibitors exhibits excellent potency in in vitro biochemical and cell-based assays ...

Researchers found that MDMA reduces anxiety and enhances social behavior in zebrafish by altering key neurochemical systems.

Treatment. Early diagnosis and prompt initiation of treatment are important in the treatment of serotonin syndrome. Management strategies include elimination of the precipitating agents and ...

The patient was then admitted to the neurotrauma intensive care unit (NTICU) with a diagnosis of serotonin syndrome and rhabdomyolysis. Supportive measures including sedation, ...

Some antidepressants can worsen the effects of hot weather. Here’s what a doctor wants you to know and how to keep yourself ...

The deprivation syndrome has also been described for SSRIs that might cause nausea, dizziness, anxiety, trembling, and heartbeat. The selective serotonin reuptake inhibitors are inhibitors of liver ...

Background and aims: The mechanisms underlying intestinal secretion in rotavirus diarrhoea remain to be established. We previously reported that rotavirus evokes intestinal fluid and electrolyte ...

Sertraline, a specific SSRI, increases the availability of serotonin, which is crucial for mood regulation. Additionally, sertraline indirectly affects dopamine neurotransmission by modulating 5-HT2A ...

For Penn researcher and her son, new center focused on Williams syndrome has special meaning 02:32. A new specialty center opened Tuesday at the Hospital of the University of Pennsylvania in ...

Introduction: Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment of irritable bowel syndrome (IBS) although evidence of their efficacy is scarce. Aim: Twenty three ...