RNA splicing is a modification of the nascent ... and associated proteins, but there are also self-splicing introns. Cryo-EM structures of circularly permuted group II introns determined at ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Other ribozymes include self-splicing introns and the RNA component of the enzyme telomerase. Non-coding RNA molecules, such as miRNAs (miRNAs) and long non-coding RNAs (lncRNAs), play essential roles ...

RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence motif, the RBP binds to the ...

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Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

mRNA splicing is a fundamental part of the process that occurs when encoded DNA instructions are turned into a functional protein. After a gene is transcribed from DNA to RNA, extraneous sections ...

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect ...