In clinical breast cancer samples, the expression of SRSF1 was upregulated and positively correlated with tumor grade, Ki-67 expression and poor prognosis. SRSF1 promoted the proliferation and ...

This cover highlights the article PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division by M. Gobran, P. Lenart and colleagues. HeLa Kyoto ...

The fit between a splice site and the spliceosome components that bind it influences splicing activity. Strong splice sites closely match consensus sequences and are efficiently recognized by the ...

The inclusion of a specific exon in the ATG5 mRNA, which is promoted by the splicing factor SRSF1, results in increased autophagy activity and decreased PASMC apoptosis (91). SRSF3 has been shown to ...

There is mounting evidence that microbes residing in the human intestine contribute to diverse alcohol-associated liver diseases (ALD) including the most deadly form known as alcohol-associated ...