Sudemycin K, a derivative that replaces the pharmacophore’s oxycarbonyl by an amide group, displays improved potency as an inhibitor of cancer cell proliferation, as a regulator of alternative ...

E2-mediated SRSF1 upregulation during the late phase of the virus replication cycle is necessary for expression of the virus capsid proteins [71] [Graham, Unpublished Observations] and therefore ...

KEGG analysis of the upregulated genes revealed enrichment in pathways including spliceosome, oxidative phosphorylation, peroxisome activity, cytochrome P450, proteasome, and thiamine ...

The spliceosome is a complex ribonucleoprotein machine that is responsible for the maturation of cellular pre-mRNAs by removing introns and ligating together the surrounding coding regions, called ...