Ferroptosis, a form of regulatory non-apoptotic cell death driven by iron-dependent lipid peroxidation, accounts for more than 80% of the total types of neuronal death in the acute phase of ...

Mitochondria were centrifuged at 2,000 g for 20 min at 4°C, then 50 μL/well assay solution was supplemented with succinate, rotenone, ADP, and MitoSOX Red (final concentrations 10 mmol/L, 2 ...

Panelists discuss potential changes to clinical pathways for Bruton tyrosine kinase (BTK) inhibitor therapies as a result of the Inflation Reduction Act (IRA), focusing on how shifting costs and ...

Next, experts said, discussions will focus on other decisions, such as when and whether to prescribe the SGLT2 inhibitors with GLP-1 receptor agonists for the best outcomes. The Path From Glucose ...

Once rotenone is introduced to a section of water, fish absorb it through their gills, causing them to suffocate. Rotenone doesn’t discriminate between native and non-native fish, so it must be ...

The Food and Drug Administration (FDA) has granted Orphan Drug designation to NS-229 for the treatment of eosinophilic granulomatosis with polyangiitis (EGPA). EGPA is a rare autoimmune disease ...

CHICAGO — In a phase 2b study, treatment with a once-daily oral PCSK9 inhibitor added to statin therapy resulted in a more than 50% reduction in LDL cholesterol at 12 weeks in patients with ...

Patients who received the lower dose of the TYK2 inhibitor had a 47.5% reduction in the CLASI-A score, which also met the pre-specified level of statistical significance of P <0.1 (P =0.0670).

Rats treated with rotenone took a longer time (P<0.001) and had difficulty initiating movements. Rotenone-induced difficulties were improved in rats treated with rotenone after sterubin administration ...

Laekna (2105.HK) announced that the U.S. Food and Drug Administration (FDA) has approved the IND for LAE120, an internally discovered USP1 inhibitor, ...

Preoperative use of SGLT2 inhibitors among patients with type 2 diabetes undergoing emergency surgery was not associated with an increased risk for postoperative diabetic ketoacidosis, a ...

Session ID: 2025-07-02:3c5c4a3580716f82bd600df Player Element ID: vjs_video_3 ...