4um of Oligomycin, 0.5um of FCCP, 1um of Antimycin A and Rotenone were injected into the cells at different ... with an extracellular flux analyser (Seahorse Bioscience). Similar inhibitor ...

To analyze oxidative phosphorylation following inhibitors were injected: oligomycin (1 µM; Cayman Chemicals), FCCP (2 µM; Cayman Chemicals), antimycin A (1 µM; Sigma-Aldrich), and Rotenone (1 µM; ...

Neutrophils were treated with inhibitors of mitochondrial respiration (rotenone/anti-mycin A) followed by 160 nM phorbol 12-myristate 13-acetate (PMA) to generate a respiratory burst.30 Oxygen ...

Calcineurin inhibitors are topical and systemic immunosuppressants. They can help treat atopic dermatitis and autoimmune disorders such as lupus and psoriasis. They may also help prevent organ ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mitochondria harbor respiratory complexes that ...

mTOR and AMPK regulates the initiation process with AMPK acting as an activator while mTOR acts as an inhibitor. Under cellular stress, mTOR reduces its inhibition on the ULK1-FIP200-ATG13 complex, ...

Objective Dysregulated cellular metabolism is a distinct hallmark of human colorectal cancer (CRC). However, metabolic programme rewiring during tumour progression has yet to be fully understood.