Rett syndrome is caused by mutations of the MECP2 gene located on the X chromosome. Children with Rett initially show typical ...

Rett syndrome is a devastating neurological disorder caused mainly by mutations in the MECP2 gene found on the X chromosome. The disease causes deficits in brain function that lead to behavioural ...

For example, some of the mutations behind Rett syndrome, a rare neurodevelopmental disorder, prevent a specific protein from binding to DNA. This process would normally enable the protein to turn ...

Rett syndrome is a devastating neurological disorder caused mainly by mutations in the MECP2 gene found on the X chromosome, so mainly affects females. It causes deficits in brain function that ...

We present the first case-control study addressing both fracture occurrence and fracture mechanisms in Rett syndrome (RTT ... CpG-binding protein 2 (MECP2) mutations. A total of 61 female ...

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego ...

Several pregnancies failed, but one female monkey born with the mutations is now several months old. Girls with Rett syndrome—which only affects females—develop motor and speech problems and ...

The long-term Phase 2/3 study demonstrated DAYBUE had a similar safety profile in children two to four years of age as that observed in individuals with Rett syndrome five years of age and older ...

Specifically, our lab is interested in Rett syndrome (RTT), a rare autism spectrum disorder (ASD) primarily affecting females, which results in motor abnormalities and social deficits. As RTT is ...