Rett syndrome is a neurodevelopmental disorder that primarily affects girls, most of whom have mutations in the transcription regulatory gene MECP2. However, mutations in MECP2 also have been ...

Taysha Gene Therapies' TSHA-102 tackles Rett syndrome’s root cause with its ... that’s also prevalent in women due to MECP2 gene mutations. This is because this particular gene is only found ...

Studies in patients with Rett syndrome revealed that mutations are almost exclusively of paternal origin. [29] The mutations in MECP2 are obviously a product of spermatogenesis, because the father ...

Rett syndrome is a devastating neurological disorder caused mainly by mutations in the MECP2 gene found on the X chromosome, so mainly affects females. It causes deficits in brain function that ...

Jones Trading initiated coverage on ProQR Therapeutics N.V. (NASDAQ:PRQR) with a Buy rating and set a price target of $11.00, representing significant upside from the current price of $2.19. The ...

Congenital heart disease (CHD) affects approximately 1% of live births. Thanks to surgical advancements, infants born with ...

People are more likely to have autism if they have related genetic disorders, such as fragile X syndrome ... the chance of spontaneous genetic mutations increases with age. There is some evidence ...

Mutations in the MECP2 gene have been recently identified as the cause of Rett syndrome, prompting research into genotype-phenotype relations. However, despite these genetic advances there has been ...