With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the natural ...

Customers looking for an mRNA therapeutic partner should prioritize operational excellence and choose flexible CDMOs.

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

Activating stem cells via molecular programming, rather than relying on random cell transplants, significantly enhances the success of regenerative treatments.

There are accumulating lines of evidence that the epigenetic modifications in DNAs, histones, and RNAs regulate RNA processing steps by influencing the transcription elongation rate of RNA polymerase ...

This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell ...

Signals from the epicardium are essential for fetal coronary lymphangiogenesis. VEGFC and VEGFD produced by the epicardium ...

RNA (ribonucleic acid) is a nucleic acid polymer where the carbohydrate is ribose. RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

This includes investigation of nuclear organization, DNA methylation, histone modification and RNA transcription. Epigenetic processes can result in intergenerational (heritable) effects as well ...