Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

It’s an honor to present these findings at the RNA Society’s 30th anniversary meeting, which highlights how RNA science is transforming patient care.” Cofactor’s presentation at the 30th Annual ...

“The different and more complex architecture allows the U11 snRNP to specifically identify its rare substrates in the vast RNA sequence landscape of every cell,” explained Zhao.

Furthermore, TSSC4 directly interacts with the SNRNP200 (U5 snRNP 200 kDa helicase) and the PRPF8 spliceosomal scaffold. During U5 snRNP or U4/U6.U5 tri-snRNP assembly and recycling, these ...

The research article, titled "Transcriptome-wide splicing network reveals specialized regulatory functions of the core spliceosome," represents a significant advancement in understanding the ...

Key Findings The study from Shandong Agricultural University found that the AtSNU13 protein is crucial for plant immunity by regulating pre-mRNA splicing in defense-related genes Plants lacking ...

Since RBM17 has only one UHM, the RBM17–SAP30BP binding has to be released before the RBM17 interaction with SF3B1, one component of U2 snRNP, that is essential to promote splicing.

The well-known essential pre-mRNA splicing factor U2AF heterodimer (U2AF2–U2AF1) has been considered to mediate early splicing reaction in all introns of different lengths. However, Dr. Kazuhiro ...

The U1 snRNP complex is essential in RNA splicing. Now, Peng and his team have demonstrated that the dysfunction of the U1 snRNP contributes to neurodegeneration, opening new avenues of research ...

The U1 snRNP complex is essential in RNA splicing. Now, Peng and his team have demonstrated that the dysfunction of the U1 snRNP contributes to neurodegeneration, opening new avenues of research ...