Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
Avidity Biosciences, Inc.'s innovative AOC platform and promising clinical programs make it a high-risk, high-reward ...
Within the cell, NOVA1’s job is to bind to RNA to regulate alternative splicing ... However, when they compared alternative splicing events in the periaqueductal gray, a midbrain region which is a key ...
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AZoLifeSciences on MSNLncRNAs, CircRNAs, and the Unseen Regulators of Gene ExpressionCircular RNAs (circRNAs) are covalently closed, highly stable, RNA loops generated through back-splicing ... to its sequence ...
Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...
Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...
RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...
Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...
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