Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

RNA splicing, a process discovered in the late 1970s ... allowing the cell to assemble the correct sequence for a desired protein. This process enables a single gene to produce multiple proteins ...

Alternative RNA splicing is similar to a movie editor cutting and rearranging scenes from the same video to produce distinct versions of a film. By deciding which sequences to keep and which to ...

California [US], March 16 (ANI): Alternative RNA splicing is similar to a movie ... By deciding which sequences to keep and which to cut, the editor can create a drama, a comedy, or even a ...

The lab of Dan Xu, PhD, assistant professor at The Hormel Institute, has published a groundbreaking study in Cell Metabolism, ...

Amid readouts from the Muscular Dystrophy Association’s annual meeting, the Clinical Trials Arena evaluates five Duchenne trials in 2025.

Emerging evidence suggests that some variants, which are described as missense, synonymous or nonsense variants in the literature or databases, may be deleterious by affecting the pre-mRNA splicing ...

This process is known as splicing. Ultimately, the spliced messenger RNA consists of only protein-encoding exons. Splicing is catalyzed by a large molecular machine. This spliceosome is made up of ...

This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.