In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

Specific RNA Sequences Are Required for Regulation of Alternative Splicing If we want to understand the splice code, then we need to analyze the existing information about constitutive and ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence motif, the RBP binds to the ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...

Splicing is a basic requirement for producing ... they are first copied into precursors of mRNA, or messenger RNA. The spliceosome then converts them into mature, functional mRNA.

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...