Quality assurance in the cell: Preventing defective protein blueprints
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
Technology Networks8d
Structural Insights Into the Cell's Quality Control Machinery
They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...
eLife16d
Generative modeling for RNA splicing predictions and design
Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
Nature18d
RNA quality control articles from across Nature Portfolio
RNA quality control is the active process by ... Proper splicing requires efficient spliceosome assembly. Here the authors reveal that zinc finger protein 207 interacts with the U1 small nuclear ...
Phys.org19d
RNA origami technique folds nanotubes to create artificial cytoskeletons for synthetic cells
Get Instant Summarized Text (Gist) RNA origami has been used to create nanotubes that form cytoskeleton-like structures, a key step in developing synthetic cells. This technique bypasses the need ...
earth26d
Plants have an amazing ability to 'rewire' themselves to survive winter
However, PORCUPINE is not just a passive responder. It actively participates in the spliceosome, a complex that processes RNA before it transforms into proteins. PORCUPINE is not just a responder to ...