Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

This process is controlled by a large protein-RNA complex called the spliceosome. MIT biologists have now discovered a new ...

Spliceosomes are large and dynamic RNA-protein complexes. The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read “snurps”) – ...

They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...

Then the RNA binding protein communicates to the splicing machinery to include or not include the exon into the mRNA,” Cooper explained. The fit between a splice site and the spliceosome components ...

We study minor spliceosome which is a parallel pre-mRNA splicing machinery in the cells of most metazoan organisms. Our main aim is to investigate mechanism and regulation of this nuclear machinery, ...

On the one hand, colder temperatures increase the amount of PORCUPINE RNA in cells, suggesting that more of the protein is produced. On the other hand, this protein is part of the spliceosome ...

Ultimately, the spliced messenger RNA consists of only protein-encoding exons. Splicing is catalyzed by a large molecular machine. This spliceosome is made up of variety of protein and RNA ...