C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic information from DNA to messenger RNA (mRNA). As there are more than 700 ...

Linda brings more than 20 years of financial, operational and executive leadership success at innovative life science companies,” said Matt Patterson, Chairman of Remix Therapeutics Board of Directors ...

Additionally, they note connections between TIGR-Tas systems and certain RNA-processing proteins in human cells. "I think ...

Scientists have attempted to map the human cell since the first microscope was invented more than 400 years ago. But many ...

Understanding RNA Processing Kinetoplastids have helped scientists understand RNA processing events, such as RNA editing. To date, gene expression resulting from RNA editing has been described in ...

which binds to specific promoter regions on the DNA and initiates the synthesis of the complementary RNA strand. The resulting primary transcript, known as pre-mRNA in eukaryotes, undergoes several ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny ...

Widespread alterations in RNA processing (splicing, polyadenylation, decay, etc.) are common in dynamic cell states during development and malignancy. For example, many cancers harbor elevated levels ...

We study minor spliceosome which is a parallel pre-mRNA splicing machinery in the cells of most metazoan organisms. Our main aim is to investigate mechanism and regulation of this nuclear machinery, ...

which influences RNA processing, stability, and translation into proteins. However, its role in cancer—particularly prostate cancer—has not been fully understood. By focusing on m 6 A ...