Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells, Cell (2019). Guanshi Wang, Jesse Hauver, Zachary Thomas, Seth A. Darst, Alexandros Pertsinidis.

Transcription is the process by which an RNA polymerase synthesizes ribonucleic ... Here they show that SSUP-72/PINN-1 regulates Pol II 3′ pausing and transcription termination in C.

Laboratory of Human Genetics & Therapeutics, Smart Health Initiative, Division of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST ...

Could these hypothetical organisms wreak havoc on the world if biologists manage to create them? After a collective of scientists called for a worldwide debate in 'Science,' Le Monde took stock of ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns, splicing ...

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.