Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Fully cell-free process aims to democratize personalized cancer therapeutics with shorter turnaround and negligible bioburden ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

In this episode presented by Eclipsebio, BioSpace's head of insights Lori Ellis discusses mRNA and srRNA with Andy Geall of ...

If a gene is evolutionarily conserved, that shows it must be doing something important. Otherwise, nature would let it go.

Liquid biopsies are tests that detect signs of cancer through a simple blood draw. Unlike traditional biopsies, which require ...

Look inside a brain cell with Huntington's disease or ALS and you are likely to find RNA clumped together.These solid-like clusters ...

Scientists have created an artificial RNA system that can copy itself using simple building blocks and temperature changes.

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

Phosphorus forms the backbone of DNA, RNA, and cellular membranes. But scientists have struggled to pinpoint the specific conditions under which ...

Both TEGSEDI and WAYLIVRA are legacy assets that were originally brought to the EU market via an Ionis subsidiary, Akcea ...