For example, many types of RNA have been found to be catalytic--that is, they carry out biochemical reactions just like enzymes do. Furthermore, many other varieties of RNA have been found to have ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

RNA abundance is regulated by balancing transcription and degradation in processes that control the temporal and spatial distribution of cellular RNA. In eukaryotic cells, mRNA decay is catalyzed by ...

Some RNA molecules, called ribozymes, possess catalytic activity and can catalyze chemical reactions. For example, the ribosome itself is a ribozyme, as the rRNA component catalyzes the formation of ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

This discovery led to the concept of the ribosome as a ribozyme, an RNA molecule with enzymatic properties. The catalytic center of the ribosome, known as the peptidyl transferase center (PTC), is ...

This is the structure of deoxyribozyme 9DB1, where we can see the synthetic strand of DNA (in green) once it has catalyzed the ligation of two RNA strands (in orange), joined at the point which is ...

Additional areas include RNA-mediated events ranging from cofactor recognition by riboswitches, catalysis by ribozymes and protein-RNA recognition events impacting on disease syndromes and the ...

We are also exploring novel methods for the detection of residual dipolar couplings (RDCs) which assist in determining the correct global structure of an RNA. Ribozymes are catalytic RNAs that perform ...