Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

Unfortunately, there isn't an enzyme for many reactions we would sorely like to catalyze—things like digesting plastics or ...

Peptides act as signal mediators in the body and are on the rise as therapeutic agents. However, their full potential can ...

The DeGregorio Family Foundation with support from the Torrey Coast Foundation Gastro Esophageal Investigator Network Initiative (GEMINI) has awarded the $125,000 to Timothy C. Wang, MD, Chief, ...

The mechanism of action (MoA) of SAB-142 was shown to be analogous to rabbit ATG. The SAB-142 MoA was shown to be analogous to rabbit ATG across multiple parameters correlative to C-peptide ...

Cys2101 in RR5 forms an intermolecular disulfide bond for dimer formation. When His3448 is substituted to Arg, Reelin activity is augmented. Studies on the mechanism regulating Reelin expression were ...

When companies or other entities such as governments need to raise money for new projects, fund operations, or refinance existing debts, they may issue bonds directly to investors. Many corporate ...

Researchers from the Institute of Science Tokyo and Osaka Medical and Pharmaceutical University said that they have developed a peptide that can bind to the spike proteins of SARS-CoV-2 to prevent ...

Lipidated analogues of glucagon-like peptide 1 (GLP-1) have gained enormous attention ... often showed multiple steps and did not follow a standard nucleation-propagation mechanism. A wide range of ...

School of Physics & Astronomy, Cardiff University, 4 The Parade, Cardiff CF24 3AA, U.K. Rufus Scientific, Melbourn, Herts SG8 6ED, U.K. Nanoplanet Consulting, Concord ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

Cleavage events where the precursor Aβ peptide level was zero (i.e., no detected coproduct ... Focusing on FAD could simplify identification of pathogenic mechanisms, as these rare variants of AD are ...