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Aligned stem cell sheets boost protein production for improved tissue repair
Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune ...
IEEE3d
Influence of Iron Oxide Nanoparticles on Innate and Genetically Modified Secretion Profiles of Mesenchymal Stem Cells - IEEE Xplore
Mesenchymal stem cells (MSCs) have well-established paracrine effects that are proving to be therapeutically useful. This potential is based on the ability of MSCs to secrete a range of ...
C&EN6d
Radiation-Induced Endothelial Inflammation Is Transferred via the Secretome to Recipient Cells in a STAT-Mediated Process | Journal of Proteome Research - ACS Publications
Radiation is the most common treatment of cancer. Minimizing the normal tissue injury, especially the damage to vascular endothelium, remains a challenge. This study aimed to analyze direct and ...
C&EN16d
Specific Stimulation and Multiplex Secretion Analysis of T Cells Using a Suspendable Hydrogel Platform Enables Immunophenotyping at the Single-Cell Scale - ACS Publications
The ability to characterize and separate cells based on their surface marker expression profiles using flow cytometry revolutionized our understanding of the immune system at the level of single cells ...
lupus.bmj26d
P17 Autophagy- based unconventional secretion of B cell activating factor (BAFF) by monocytes in Systemic Lupus Erythematosus (SLE) - Lupus Science & Medicine
Objective CD14+ monocytes, play pivotal role, in SLE pathogenesis through enhanced production of B-cell activating factor (BAFF), a major cytokine driving B-cell maturation into ...