Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain ...

The results of experiments in mice models were "astounding," said biochemist Suzanne Pfeffer of Stanford University.

Original Paper Published: 21 July 2000 Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis Lily Yen, Xiao-Li You, Ala-Eddin ...

The PPIs selectively and irreversibly inhibit the gastric H + /K + -exchanging ATPase ('proton pump'). Inactivation of this enzyme system blocks the final step of acid secretion by parietal cells, ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

The ability to characterize and separate cells based on their surface marker expression profiles using flow cytometry revolutionized our understanding of the immune system at the level of single cells ...

Two experiments were undertaken in dogs to discover the influence of cortisone on the parietal cell population of the stomach. In one, samples of mucosa were removed at operation before and after the ...

Suspension of magnesium and aluminum hydroxide (30--60 mEq/24h) or a comparable volme of water was orally administered by gastric intubation to two groups of 20 male Wistar rats each over 60 days. The ...

Objective CD14+ monocytes, play pivotal role, in SLE pathogenesis through enhanced production of B-cell activating factor (BAFF), a major cytokine driving B-cell maturation into ...

Radiation is the most common treatment of cancer. Minimizing the normal tissue injury, especially the damage to vascular endothelium, remains a challenge. This study aimed to analyze direct and ...

Cells were rinsed two times in 1X PBS followed by membrane permeabilization for 10 min in 0.3% Triton-X-100 (Sigma Aldrich #T8787) in 1X PBS. Cells were then rinsed two times in 1X PBS followed by ...