Laboratory Investigation - Glomerular parietal epithelial cell activation induces collagen secretion and thickening of Bowman’s capsule in diabetes Skip to main content Thank you for visiting ...

The selective failure of intrinsic-factor secretion in the presence of continued acid secretion is of particular interest in view of the recent observation that human parietal cells apparently ...

In the stomach, so-called parietal cells are responsible for acid production. They react not only to the body's own messenger molecules, but also to bitter-tasting food constituents such as caffeine.

Parietal cells are present in the gastric pits that mainly occur in the upper part of the stomach, ... Serotonin is involved in regulating gastrointestinal motility and fluid secretion. P/D1 cells ...

Vonoprazan suppresses basal and stimulated gastric acid secretion at the secretory surface of the gastric parietal cell through inhibition of the H +, K +-ATPase enzyme system in a potassium ...

Colin Howden, MD, discusses the mechanisms at work in vonoprazan as well as patient monitoring and potential future uses following a recent FDA approval for the treatment of erosive esophagitis.