Researchers at the Francis Crick Institute have demonstrated that a genetic method called "pooled prime editing" can screen ...

Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...

Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. GA, UNITED STA ...

Men who experienced abuse or neglect in childhood show distinct changes in the molecular makeup of their sperm, according to ...

and the complexes of LncRNAs and proteins are localised to the DNA sequences of the downstream genes LINC00618 binds to LSH and inhibits the transcription of SLC7A11, thus further promoting ...

Key epigenetic mechanisms—such as DNA methylation, histone modifications, and the involvement of noncoding RNAs—regulate cccDNA activity. For example, DNA methylation suppresses viral transcription, ...

Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development of gastric cancer-among the world's deadliest forms of the disease.

The main function of RNA is to convert genetic information from DNA into proteins. Non-coding RNA molecules don't carry genetic information that would later be converted to proteins. "We discovered ...

The small study in patients with a rare disorder that causes liver and lung damage showed the potential for precisely targeted infusions. By Gina Kolata Researchers have corrected a disease ...

Cosmic rays from a nearby supernova would soon rain down on the unsuspecting cichlids, tearing apart their DNA, causing the fish to mutate and opening the door for myriad viruses to infect their ...