It can also make sense of existing DNA, including hard-to-interpret ‘non-coding’ gene variants that are linked to disease. ‘ChatGPT for CRISPR’ creates new gene-editing tools Evo 2 ...

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

It’s time to shine a light on the next wave of drug discovery.

Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development ...

Swiss start-up Haya Therapeutics has formed a partnership with Eli Lilly – worth up to $1 billion – to look for new therapies for obesity in non-coding DNA. The biotech focuses on trawling the ...

Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Professor and HHMI Investigator Zachary Lippman and his colleagues have begun to uncover the ways in which fragments of non-coding DNA called cis-regulatory sequences dictate how, when ...

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...

With further testing, discovery may offer new target for early detection and treatmentResearchers at Case Western Reserve ...