Superoxide overproduction is known to occur in multiple disease states requiring critical care; yet, noninvasive detection of superoxide in deep tissue remains a challenge. Herein, we report a ...

We have designed and developed pH-sensitive nanoparticle possessing nitroxyl radicals in the core and acetal groups as a platform moiety to install ligand molecules on the periphery, which ...

Professor Eaton’s funding will enable him and his team to investigate the preventive role the molecule nitroxyl can have for cardiovascular disease. Nitroxyl is formed in cells, and drugs are ...

16 August 2022 Image: iStock A new study led by Monash University researchers has, for the first time, shown that the chemical compound 'nitroxyl' may represent an effective and rapid intervention for ...

A new study led by Monash University researchers has, for the first time, shown that the chemical compound 'nitroxyl' may represent an effective and rapid intervention for cardiovascular emergencies ...

Background: We previously demonstrated that nitroxyl causes vasodilation, at least in part, by inducing the formation of an intradisulfide bond between C117 and C195 in the high affinity cyclic ...

"In nitroxyl‐based polymers the only charge‐transport pathway is electron hopping between adjacent redox centers, which is fast on the microscopic scale," the researchers explain in their study.

The molecules of this metallopolymer act as a molecular wire to which energy-intensive nitroxyl pendants are attached. The molecular architecture of the material enables high capacitance performance ...

Since 2016, a group of scientists at Russia’s St. Petersburg University has investigated a group of materials known as redox-active nitroxyl-containing polymers.

Nitroxyl is highly thiophilic and may interact with thiol groups. In the presence of DTT (500 μM), known to maintain SH groups in reduced state or reduce protein disulfide bonds, the relaxing property ...