Erectile dysfunction drugs should't be taken with nitrates, which are used for chest pain. Research from Denmark suggests some men are able to take both safely.

Nitrates may make you feel dizzy. You may also get a rapid, irregular, or pounding heartbeat when you take the drugs regularly. It usually gets better after the first few weeks.

The number of nitrate users who had also been prescribed an ED drug rose dramatically during that period, from 0.9 prescriptions per 100 patients in 2000 to 19.5 per 100 in 2018.

The analysis included 61,487 men, of whom 9% had filled prescriptions for a PDE5 inhibitor. Compared with men treated with nitrates alone, those who had prescriptions for both types of drugs were ...

Taking ED drugs and nitrates at the same time effectively doubles their blood-vessel dilating effects, potentially resulting in an extreme drop in blood pressure. The study analyzed data from ...

Among 55,777 men with a history of previous myocardial infarction (MI) or coronary revascularization who had filled at least two nitrate prescriptions (sublingual, oral, or both), 5710 also had at ...

But in a new study of more than 60,000 men, taking this medication along with nitrates, a common drug for chest pain, increased risks of negative health outcomes such as heart failure and early ...

Compared with nitrate users not on phosphodiesterase-5 (PDE5) inhibitor treatment for ED, those who had both types of drugs in their medication history tended to be at higher risk for events over ...

The men who used nitrates and PDE5i were younger (mean age, 61.2) than those who used only nitrates (mean age, 70.3). Overall, mortality occurred among 43% of the nitrate group compared with 10.4% ...

It's best to use nitrite drugs only when and as your doctor prescribes them. If you use nitrite drugs outside of their intended medical use, b e aware of these risks: Never swallow or eat the liquid.