By applying advanced structural biology techniques, Kovalev discovered that the secret to their blue color is the same rare ...

Imagine the magnificent glaciers of Greenland, the eternal snow of the Tibetan high mountains, and the permanently ice-cold ...

Master the art of identifying small molecules through mass spectrometry. Join our course for hands-on training in data ...

Collagen IV provides crucial structural support for cells and tissues, but it’s unstable at body temperature. Researchers now ...

Reducing our intake of a single amino acid called methionine, which we get from the food we eat, could help protect against ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living cells - using the cells' own components as built-in sensors.

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

The active sites of hundreds of human α-ketoglutarate (αKG) and Fe(II)-dependent dioxygenases are exceedingly well preserved, which challenges the design of selective inhibitors. We identified a ...

Drs Olga Brieieva and Martin Higgs discuss in vitro genomic models for predicting clinical resistance to PARP inhibitors for ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Mechanistically, HCC cells outcompeted T cells for lysine by expressing high levels of the lysine transporter solute carrier family 3 member 2 (SLC3A2). Clinically, elevated SLC3A2 expression ...