Fintel reports that on March 17, 2025, Leerink Partners initiated coverage of Nurix Therapeutics (NasdaqGM:NRIX) with a ...

The second is KBTBD4, which is part of a class of protein complexes called E3 ubiquitin ligases 5. These enzymes catalyse the addition of a ubiquitin protein to other proteins, marking them for ...

E2 conjugating enzymes, E3 ligases, and deubiquitinase enzymes, which are crucial for the development of innovative therapeutics. Never miss a story ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), ...

The applied physicist explains how the structure of 52,000-year-old genes hint at the biology of an extinct animal ...

Digestive enzymes, for instance, belong to the hydrolase category and help break down foods to make them more easily absorbed throughout the body. There's also metabolic enzymes, which belong to the ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

Including 2023 enzyme sales related to PAXLOVIDTM ... such as its ECO SynthesisTM manufacturing platform and dsRNA ligase; Codexis' dependence on a limited number of products and customers ...

Parkin, an E3 ubiquitin ligase, is recruited to the outer mitochondrial ... between wild-type and double knockouts. TCA cycle enzyme activities and mitochondrial respiration rates remained ...

ligands for E3 ligases, enzymes involved in the control of protein levels in cells. San Diego, California-based Cullgen – led by Shanghai Genomics' founder, Ying Luo – says the discovery ...

This labelling process requires three types of enzymes working in sequence. E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure ...