When a child develops a brain tumor, early diagnosis is essential. Alan Cohen, M.D., director of pediatric neurosurgery at Johns Hopkins Children’s Center, shares the most common signs and symptoms ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings, blocking the body’s immune defenses and creating a sort of haven ...

Radiation therapy, as well as having a close relative who has had a brain tumor, can also slightly increase a person's risk of developing the disease. Treatment for brain tumors depends on the ...

For 3 out of every hundred people with cancer, the primary site of cancer isn't found. When this is the case, the tumor is usually referred to as a metastatic cancer of unknown primary origin. With ...

We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy. Emerging strategies, such as logic-gated and dual-targeting ...

Krukenberg tumors are bilateral in 80% of cases. When large, these lesions are more likely to be cystic and bilateral. The ovarian neoplasms are actually discovered prior to the primary tumor in ...

Each child’s outlook can vary based on factors specific to them. The most important factors in determining a child’s outlook are the stage and histology of the tumor. (Histology refers to how the ...

Wilms tumor (also called nephroblastoma) is the most common type of kidney cancer in children. About 9 of 10 kidney cancers in children are Wilms tumors. These cancers are different from adult kidney ...