Researchers have unveiled a novel immune mechanism by which tandem kinases combat pathogen invasion: an atypical NLR protein, ...

A catalytic mechanism is the sequence of elementary reactions by which a catalytic reaction proceeds. Ruthenium-based catalysts are of interest for ammonia synthesis, however they are susceptible ...

especially the mechanisms by which transmembrane receptors bind specific attractants and regulate the output kinase activity. This kinase activity controls the swimming motor and cellular migration up ...

The phosphoinositide 3-kinase (PI3K) pathway is a crucial signal transduction system linking the activation of receptor tyrosine kinases (RTKs), G protein-coupled receptors (GPCRs) and oncogenes ...

Protein kinase inhibitors have therefore ... shed light on TIM-063's binding to AAK1's catalytic domain, offering insights into its inhibitory mechanism. By elucidating the binding of TIM-063 ...

About Nuvectis Pharma, Inc. Nuvectis Pharma, Inc. is a biopharmaceutical company focused on the development of innovative precision medicines for the treatment of serious conditions of unmet medical ...

A research team led by Prof. LIU Zhiyong from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, together with collaborators, has uncovered a novel immune ...