Exon skipping, on the other hand, occurs when the spliceosome skips an exon to allow an mRNA to be produced albeit with an altered coding sequence. ‘Decoy’ exons also occur. Although their mode of ...

The Role of the Spliceosome. Splicing is catalyzed by a large molecular machine. This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled ...

This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an exon joins an intron and the intron in turn connects to ...

This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an exon joins an intron and the intron in turn connects to ...

Then, the splicing machinery (spliceosome) locates the exon-intron boundaries, precisely removes the introns, and joins the appropriate exons, generating the spliced mRNA.

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Intron function . While introns, for some time, ... Another theory is that the spliceosome and the intron-exon structure of genes is a relic of the RNA world hypothesis, which suggests that all life ...

Exons and introns were quantified using uniquely mapped reads on the basis of the reannotated GTF file using HTseq. 26 IR events were further filtered using the following criteria: (1) both the intron ...