Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
News Medical on MSN5d
Understanding the role of alternative splicing in cardiovascular diseasesAnnouncing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...
News Medical on MSN2d
Splicing twins: unravelling the secrets of the minor spliceosome complexHuman genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
AZoLifeSciences on MSN18h
Understanding the Complex Architecture of the Minor SpliceosomeIn human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...
SMN1 brings together the complex and is essential for spliceosome assembly. Since motor neurons are particularly sensitive to SMN1 mutations, additional roles for the SMN complex in these cells are ...
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