Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...

Stargardt disease type 1 (STGD1) is an inherited retinal recessive disease caused by biallelic variants in the ABCA4 gene. One of the recurrent variants is located at the exon-intron junction of exon ...

A self-described “classic nerd,” Tomberg began running some experiments of her own to try “to figure out what makes an intron from ... that indicate good splicing and bad splicing.

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

“Our work provides exciting new insights into the mechanism of minor intron recognition and sheds light on the evolution of the splicing machinery. It opens up new possibilities for studying ...