Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

Boehringer will leverage ExpressionEdits' Genetic Syntax Engine which generates optimized introns to increase protein expression.

Their OGT intron 4 reporter reliably responds to O-GlcNAc levels, mirroring the endogenous splicing event. Through a genome-wide CRISPR knockout library, they uncover a range of splicing-related genes ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

His lab slowed the splicing process in yeast cells, and discovered that after the spliceosome released the mRNA that it had finished splicing introns from, it hung onto intron lariats and reshaped ...

Pre-tRNA is converted into mature tRNA, which has a complex 3D structure, through a series of steps, including the excision of an intron by specific endonucleases. In humans, this is catalyzed by the ...

The Bradley lab was interested in charting new territory by now searching for recursive splice sites in shorter intron regions within human genes. Due to the connection between long introns and ...

Increased minor spliceosome activity is associated with prostate cancer progression Minor intron-containing genes are overrepresented as direct interactors with oncogenes Minor splicing alters splice ...

iNtRON Biotechnology has announced that the Tech Transfer process of SAL200, endolysin-based new biologic, is in the final stage.