Abnormal kinase signaling can promote other harmful traits, such as neuroinflammation and neuronal cell death. On the other ...

The brains of patients with Alzheimer's disease are characterized by the abundance of extracellular amyloid plaques and intracellular neurofibrillary tangles. The major constituent of the amyloid ...

Once amyloid pathology is underway, it predicts intracellular accumulation of hyperphosphorylated tau as neurofibrillary tangles and that, in turn, predicts onset of cognitive impairment.

While a comprehensive cure-all to these neurological conditions is unlikely, scientists are making headway into understanding ...

For example, in late-stage Alzheimer's disease, these may appear as neurofibrillary tangles. Recent research ... a direct relationship between the intracellular concentration of ATP and the ...