Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

More information: Kenji Oishi et al, MHC Class II‐Expressing Mucosal Mast Cells Promote Intestinal Mast Cell Hyperplasia in a Mouse Model of Food Allergy, Allergy (2025). DOI: 10.1111/all.

Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are excessively proliferated during food allergies, the precise mechanisms that ...

The intestinal immune system is complicated machinery ... head of the Laboratory of Mucosal Immunology. After optimizing LIPSTIC for the task, Canesso and colleagues succeeded in pinpointing ...

Study reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases.

The answer appears to lie in the balance of microbes that live in our intestine - and a specific protein secreted by intestinal goblet cells that influences that balance. Excess amounts of this ...

Normally, the intestinal mucosa acts as a protective barrier that also allows nutrients and water to pass through it. In some autoimmune diseases, the intestinal barrier may function poorly.

Increased propensity for leaky gut Normally, the intestinal mucosa act as a protective barrier that also allows nutrients and water to pass through it. In some autoimmune diseases, the intestinal ...

Successful developments will result in novel mucosal delivery systems in the nanometric range, which may be highly appreciated by therapists and patients. Components of the intestinal mucosal ...