by generating lethal DNA breaks during by transcription-coupled NER. Selection of Et743-resistant cell lines We generated two Et743-resistant derivatives of human colon carcinoma cells.

Researchers harness the power of the world’s most advanced supercomputers to simulate the inner workings of cellular ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

"This DNA repair and replication activity supports a ... snake's genetic and reproductive quirks may also provide insights into human trisomy conditions, such as Down syndrome.

The two proteins found to be mutated in this syndrome, ERCC8 and ERCC6, have been shown to be required for transcription-coupled repair. Of all the diseases listed in Table 1, Alzheimer's disease ...

This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...

Surgical repair remains the only current treatment ... With the prevalence of hypospadias on the rise, coupled with the challenges of surgical treatment, a deeper understanding of its molecular ...

Human papillomavirus (HPV ... RNA-based HPV diagnostics and the role of E6/E7 mRNA detection as a predictive marker for the development of cervical carcinoma. HPV E6/E7 mRNA testing for high ...

Ultimately, choosing a transcription service comes down to cost, whether it is a human or computer doing the transcribing, and the other integrated services. With the basics laid out, here are the ...

The researchers then measured the repair of oxidative DNA damage by analyzing levels of a marker known as 8-hydroxy-2′-deoxyguanosine (8-OH-dG) in urine samples. Higher levels of this marker ...