The nucleosomes are made up of viral DNA 'strings' and 'beads' of DNA-organizing histones, which are provided by host cells. While the packaging and organization of DNA might seem to oppose gene ...

Chemical modification of DNA or of chromatin-associated proteins, particularly histones, has a major influence ... can affect histone modification in overlying nucleosomes in a process that ...

All histones were purified using the method described previously ... with biotin-14-dATP 72. The nucleosomes were assembled with the salt dialysis method 72. Purified DNAs were mixed with H3-H4 and ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

To clarify the association between certain immunologic factors and clinical activity in patients with systemic lupus erythematosus, 96 patients were studied. Those with antibodies to ...

AppleTV is the home of the MLS Season Pass. / Matthew Ashton/Getty An MLS Season Pass is the ultimate way to experience every moment of the 2025 Major League Soccer season. Available on Apple TV ...

As the old adage goes, “When it rains, it pours.” This is precisely the case for residents and businesses of the embattled Ditsobotla Local Municipality in the North West. Violent clashes have ...

Here we present in situ electron cryotomography analyses of chromatin in both G1 and metaphase RPE-1 cells. G1 nucleosomes are concentrated in globular chromatin domains, and metaphase nucleosomes are ...

The “Histones and Chromatin” Review series published in EMBO Reports and The EMBO Journal includes six reviews centered around the histone code hypothesis. The reviews focus on histone variants and ...