Quality assurance in the cell: Preventing defective protein blueprints
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
Technology Networks20h
Structural Insights Into the Cell's Quality Control Machinery
They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...
Mirage News4h
Cell's Quality Check: Stopping Defective Protein Plans
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA – a prerequisite for ...
Indiatimes3d
Group-I aspirants petition Telangana HC over evaluation process
Over 20 Group I aspirants from Telangana sought the High Court's intervention regarding the TSPSC's evaluation process, alleging unfair assessment due to the lack of subject experts, contrary to a ...
The New Indian Express20d
Long-awaited TGPSC Group-I exam results on March 10
HYDERABAD: The long-awaited Telangana Public Commission Public Service (TGPSC) Group-I examination results are set to be declared on March 10. TGPSC issued a notification on Friday stating that ...
eLife8d
Generative modeling for RNA splicing predictions and design
Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...
EMBO Press4d
Induction of a transcriptional adaptation response by RNA destabilization events
This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.
eLife10d
Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...