A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical ...

Researchers have engineered yeast to efficiently convert methanol into D-lactic acid, a key compound for biodegradable plastics and pharmaceuticals. By optimizing gene and promoter combinations, they ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Great recipes require the perfect combination of ingredients—biotechnology recipes are no exception. Researchers from Osaka ...

Here, the authors use a proteomics-based fishing-for-partners approach to profile the interactors of G4-forming DNA sequences from the promoter regions of four cancer-related genes, identifying 86 ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ... Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be ...

Their clinical AD data analysis began with a GWAS on a clinical AD cohort in which nearly half of participants had non-European ancestry, the dataset from the National Institute on Aging Genetics of ...

Sequence variations in drug disposition genes can alter the pharmacokinetics of a drug, while sequence variations in drug target genes can change the pharmacodynamics of the drug. The two most ...

Impact and progress Frontiers' impact Progress Report 2022 All annual reports ...